Pharmxim

 (Cefixime)

Harrison's Internal Medicine

Cefixime is effective for MDR enteric fever.

Ref: Harrison's Internal Medicine 17th Edition.,2008.

Management of Enteric Fever

100 mg/5ml

200 mg/5ml

 

LOW MIC (mg/m1)

Salmonella spp ..... 0.05-0.2

...100% susceptibility against causative pathogens2.

 

High Tissues Concentration3

Bile……….   199.3 (lg/m1)

Gall Bladder……..    25.02 (pg/mI)

 ... less relapse rate2.

 

Fight against MDR Strains in routine & complicated infections

 

PROVEN CLINICAL EFFICACY

•Pneumonia                           98.9%

•Otitis Media                         98.45

•Pharyngit/Tonsillitis             98%    

•Bronchitis                             95%

•Enteric Fever                        95%

•UTI's                                      90%

 

 

 

 

BRIEF PRESCRIBING INFORMATION:

•Presentation:Fine Granules for pediatric oral suspension.

•Pharmxim (Susp):Contains Cefixime 100 mg in each 5ml.Volume of reconstituted pineapple flavored suspemsion is available in pack of 30 ml.

•Pharmxim(Caps):Each capsule contains 400 mg of Cefixime,available in alu alu pack of capsules.

•Indications:Upper respiratory tract infections,Lower respiratory Tract Infections,Genito-urinary infections,Bacterial gastro enteritis and Typhoid fever.

•Dosage & Administration:The recommended dosage for children is 8 mg/kg/dayu,administered as single dose.

•For Adults: one capsule once aday.

•Contra-indicatios:Patients with known hypersensitivity tp Cephalosporins.

•Side Effects:are mild and transient.More common side eefects are Diarrhoea,Abdominal Pain,Nausea,Flatulence.